Phenylpropanoids and polyketides
Cinnamic acids and derivatives
(938)
Flavonoids
(928)
Linear 1 3-diarylpropanoids
(804)
Coumarins and derivatives
(714)
Depsides and depsidones
(521)
Phenylpropanoic acids
(346)
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Medchemexpress LLC 2-hydroxychalcone | 644-78-0 | 98.1% | 10MM 1ML
2-hydroxychalcone | 644-78-0 | 98.1% | 10MM 1ML
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Medchemexpress LLC Naringenin | 480-41-1 | 99.3% | 272.25 | 5 MG
Naringenin is the predominant flavanone found in Citrus reticulata Blanco. It exhibits strong anti-inflammatory and antioxidant activities, and also possesses anti-dengue virus (DENV) activity.
- Inhibits proliferation and induces apoptosis in HepG2 cells
- Reduces cell viability and increases DNA fragmentation in A431 cells
- Reduces plasma and liver triglyceride and cholesterol levels
- Lowers adiposity and triglyceride content
- Increases hepatic PPARα protein expression and enhances CPT-1 and UCP2 expression
- Boosts hepatic fatty acid oxidation and prevents sterol regulatory element-binding protein 1c-mediated lipogenesis
- Inhibits TNF-α-induced VSMC proliferation and migration
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Medchemexpress LLC Avobenzone | 70356-09-1 | 98.0% | 100 MG
Avobenzone is a dibenzoylmethane compound widely used as a UVA filter in sunscreens for skin photoprotection. It is also an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist.
- Significantly promotes adipogenesis in hBM-MSCs
- Significantly up-regulates mRNA levels of PPARγ during adipogenesis in hBM-MSCs
- Inhibits proliferative activities of human trophoblast cells and induces apoptosis in HTR8/SVneo cells
- Shows weak ERα agonism and weak AR antagonism
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Medchemexpress LLC 1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one | 149732-52-5 | 292.33 | 5 MG
1,7-Bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one is a potent nucleocapsid (N) protein inhibitor isolated from *Curcuma kwangsiensis*. It demonstrates excellent antiviral activity against HCoV-OC43 and SARS-CoV-2.
- Inhibits nucleocapsid (N) protein
- Exhibits antiviral activity against HCoV-OC43 and SARS-CoV-2
- Active against various cell lines (KB, PC-12, Vero)
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